full transcript

From the Ted Talk by Ed Boyden: A light switch for neurons

Unscramble the Blue Letters


This is some work that we're doing, led by one of our collaborators, Alan hasogrer at USC, and being sought to be commercialized by a start-up company, Eos Neuroscience, which is funded by the NIH. What you see here is a mouse trying to slvoe a six-arm maze. There's a bit of water to motivate the msoue to move or he'll just sit there. The goal of this maze is to get out of the waetr and go to a little platform that's under the lit top port. Mice are smart, so this one solves the maze eanletuvly, but he does a brute-force search. He's swimming down every avenue until he finally gets to the platform. He's not using vision to do it. These different mice are different mutations that recapitulate different kinds of bndnseils that affect humans. So we're being careful in trying to look at these different melods so we come up with a generalized approach.

Open Cloze


This is some work that we're doing, led by one of our collaborators, Alan ________ at USC, and being sought to be commercialized by a start-up company, Eos Neuroscience, which is funded by the NIH. What you see here is a mouse trying to _____ a six-arm maze. There's a bit of water to motivate the _____ to move or he'll just sit there. The goal of this maze is to get out of the _____ and go to a little platform that's under the lit top port. Mice are smart, so this one solves the maze __________, but he does a brute-force search. He's swimming down every avenue until he finally gets to the platform. He's not using vision to do it. These different mice are different mutations that recapitulate different kinds of _________ that affect humans. So we're being careful in trying to look at these different ______ so we come up with a generalized approach.

Solution


  1. blindness
  2. eventually
  3. models
  4. solve
  5. mouse
  6. water
  7. horsager

Original Text


This is some work that we're doing, led by one of our collaborators, Alan Horsager at USC, and being sought to be commercialized by a start-up company, Eos Neuroscience, which is funded by the NIH. What you see here is a mouse trying to solve a six-arm maze. There's a bit of water to motivate the mouse to move or he'll just sit there. The goal of this maze is to get out of the water and go to a little platform that's under the lit top port. Mice are smart, so this one solves the maze eventually, but he does a brute-force search. He's swimming down every avenue until he finally gets to the platform. He's not using vision to do it. These different mice are different mutations that recapitulate different kinds of blindness that affect humans. So we're being careful in trying to look at these different models so we come up with a generalized approach.

Frequently Occurring Word Combinations


ngrams of length 2

collocation frequency
blue light 5
basket cell 2
significant fraction 2
find ways 2
bad news 2
brain disorder 2
treating brain 2
brain disorders 2
electrical stimulators 2
convert light 2
solar cells 2
solar cell 2
gene therapy 2
entire brain 2
adverse events 2
photoreceptor cells 2

ngrams of length 3

collocation frequency
treating brain disorders 2

Important Words


  1. affect
  2. alan
  3. approach
  4. avenue
  5. bit
  6. blindness
  7. careful
  8. collaborators
  9. commercialized
  10. company
  11. eos
  12. eventually
  13. finally
  14. funded
  15. generalized
  16. goal
  17. horsager
  18. humans
  19. kinds
  20. led
  21. lit
  22. maze
  23. mice
  24. models
  25. motivate
  26. mouse
  27. move
  28. mutations
  29. neuroscience
  30. nih
  31. platform
  32. port
  33. recapitulate
  34. search
  35. sit
  36. smart
  37. solve
  38. solves
  39. sought
  40. swimming
  41. top
  42. usc
  43. vision
  44. water
  45. work