full transcript

From the Ted Talk by Steve McCarroll: How data is helping us unravel the mysteries of the brain

Unscramble the Blue Letters


I want to tell you a short story about a discovery we recently made about the genetics of sheohciziprna. It was made possible by 50,000 polpee from 30 countries, who contributed their DNA to genetic research on schizophrenia. It had been known for several years that the hmuan genome's largest influence on risk of schizophrenia comes from a part of the genome that encodes many of the molecules in our immune setsym. But it wasn't claer which gene was rbsenpilose. A scientist in my lab developed a new way to analyze DNA with computers, and he discovered something very surprising. He found that a gene called "complement component 4" — it's called "C4" for short — comes in dozens of different forms in different people's gnemeos, and these different fmros make different amounts of C4 protein in our brains. And he found that the more C4 protein our genes make, the greater our risk for schizophrenia.

Open Cloze


I want to tell you a short story about a discovery we recently made about the genetics of _____________. It was made possible by 50,000 ______ from 30 countries, who contributed their DNA to genetic research on schizophrenia. It had been known for several years that the _____ genome's largest influence on risk of schizophrenia comes from a part of the genome that encodes many of the molecules in our immune ______. But it wasn't _____ which gene was ___________. A scientist in my lab developed a new way to analyze DNA with computers, and he discovered something very surprising. He found that a gene called "complement component 4" — it's called "C4" for short — comes in dozens of different forms in different people's _______, and these different _____ make different amounts of C4 protein in our brains. And he found that the more C4 protein our genes make, the greater our risk for schizophrenia.

Solution


  1. system
  2. human
  3. people
  4. responsible
  5. clear
  6. forms
  7. genomes
  8. schizophrenia

Original Text


I want to tell you a short story about a discovery we recently made about the genetics of schizophrenia. It was made possible by 50,000 people from 30 countries, who contributed their DNA to genetic research on schizophrenia. It had been known for several years that the human genome's largest influence on risk of schizophrenia comes from a part of the genome that encodes many of the molecules in our immune system. But it wasn't clear which gene was responsible. A scientist in my lab developed a new way to analyze DNA with computers, and he discovered something very surprising. He found that a gene called "complement component 4" — it's called "C4" for short — comes in dozens of different forms in different people's genomes, and these different forms make different amounts of C4 protein in our brains. And he found that the more C4 protein our genes make, the greater our risk for schizophrenia.

Frequently Occurring Word Combinations


ngrams of length 2

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medical progress 2
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cellular smoothie 2
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bead delivers 2
dna bar 2
bar code 2
specific genes 2
data problem 2
immune system 2
complement proteins 2

ngrams of length 3

collocation frequency
profound medical progress 2
big data problem 2

Important Words


  1. amounts
  2. analyze
  3. brains
  4. called
  5. clear
  6. component
  7. computers
  8. contributed
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  11. discovered
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  13. dna
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  15. encodes
  16. forms
  17. gene
  18. genes
  19. genetic
  20. genetics
  21. genome
  22. genomes
  23. greater
  24. human
  25. immune
  26. influence
  27. lab
  28. largest
  29. molecules
  30. part
  31. people
  32. protein
  33. research
  34. responsible
  35. risk
  36. schizophrenia
  37. scientist
  38. short
  39. story
  40. surprising
  41. system
  42. years