full transcript

From the Ted Talk by Helen M. Farrell: What is depression?


Unscramble the Blue Letters


Depression is the leading cause of disability in the wlrod. In the United States, colse to 10% of adults struggle with depression. But because it's a mental islnles, it can be a lot harder to understand than, say, high cholesterol. One major source of confusion is the difference between having depression and just feeling depressed. Almost everyone feels down from time to time. Getting a bad grade, losing a job, having an argument, even a rainy day can bring on feelings of sadness. Sometimes there's no trigger at all. It just pops up out of the blue. Then circumstances change, and those sad feelings disappear. Clinical dieesoprsn is different. It's a medical disorder, and it won't go away just because you want it to. It lingers for at least two consecutive wekes, and significantly interferes with one's ability to work, play, or love. Depression can have a lot of different symptoms: a low mood, loss of interest in things you'd normally enojy, changes in appetite, feeling wseotrhls or ecvsesxiley guilty, sleeping either too much or too little, poor concentration, restlessness or slowness, loss of energy, or recurrent thoughts of suicide. If you have at least five of those symptoms, according to psychiatric guidelines, you qualify for a dnoisgias of depression. And it's not just behavioral symptoms. Depression has physical manifestations inside the brain. First of all, there are changes that could be seen with the naked eye and X-ray vision. These include smaller frontal lobes and haipapmpcol volumes. On a more microscale, depression is associated with a few things: the abnormal transmission or depletion of certain neurotransmitters, especially serotonin, norepinephrine, and dopamine, blunted circadian rhythms, or siicefpc changes in the REM and slow-wave parts of your sleep cycle, and hormone abnormalities, such as high cortisol and deiuerogaltn of thyroid homenors. But neuroscientists still don't have a complete ptcruie of what causes depression. It seems to have to do with a clomepx interaction between genes and environment, but we don't have a diagnostic tool that can accurately predict where or when it will show up. And because depression smopytms are intangible, it's hard to know who might look fine but is actually stnrgulgig. According to the National Institute of Mental Health, it takes the average person suffering with a maentl illness over ten years to ask for help. But there are very effective treatments. mctoieaidns and therapy complement each other to bosot brain chemicals. In extreme cases, electroconvulsive teharpy, which is like a controlled seizure in the patient's bairn, is also very helpful. Other promising treatments, like transcranial magnetic stimulation, are being investigated, too. So, if you know someone struggling with depression, encourage them, gently, to seek out some of these options. You might even offer to help with specific tasks, like looking up therapists in the area, or mkiang a list of qeunstios to ask a doctor. To someone with depression, these first steps can seem iumbsalnrnutoe. If they feel guilty or ashamed, point out that depression is a micaedl condition, just like ashtma or diabetes. It's not a waskeens or a personality trait, and they shouldn't expect themselves to just get over it anymore than they could will themselves to get over a broken arm. If you haven't experienced depression yourself, avoid comparing it to times you've felt down. Comparing what they're experiencing to normal, temporary fieengls of sadness can make them feel guilty for struggling. Even just talking about depression olepny can help. For example, research swohs that asking someone about suicidal thoughts actually reduces their suicide risk. Open conversations about mental illness help erode sigmta and make it easier for people to ask for help. And the more patients seek treatment, the more stsnicties will learn about depression, and the better the treatments will get.

Open Cloze


Depression is the leading cause of disability in the _____. In the United States, _____ to 10% of adults struggle with depression. But because it's a mental _______, it can be a lot harder to understand than, say, high cholesterol. One major source of confusion is the difference between having depression and just feeling depressed. Almost everyone feels down from time to time. Getting a bad grade, losing a job, having an argument, even a rainy day can bring on feelings of sadness. Sometimes there's no trigger at all. It just pops up out of the blue. Then circumstances change, and those sad feelings disappear. Clinical __________ is different. It's a medical disorder, and it won't go away just because you want it to. It lingers for at least two consecutive _____, and significantly interferes with one's ability to work, play, or love. Depression can have a lot of different symptoms: a low mood, loss of interest in things you'd normally _____, changes in appetite, feeling _________ or ___________ guilty, sleeping either too much or too little, poor concentration, restlessness or slowness, loss of energy, or recurrent thoughts of suicide. If you have at least five of those symptoms, according to psychiatric guidelines, you qualify for a _________ of depression. And it's not just behavioral symptoms. Depression has physical manifestations inside the brain. First of all, there are changes that could be seen with the naked eye and X-ray vision. These include smaller frontal lobes and ___________ volumes. On a more microscale, depression is associated with a few things: the abnormal transmission or depletion of certain neurotransmitters, especially serotonin, norepinephrine, and dopamine, blunted circadian rhythms, or ________ changes in the REM and slow-wave parts of your sleep cycle, and hormone abnormalities, such as high cortisol and ____________ of thyroid ________. But neuroscientists still don't have a complete _______ of what causes depression. It seems to have to do with a _______ interaction between genes and environment, but we don't have a diagnostic tool that can accurately predict where or when it will show up. And because depression ________ are intangible, it's hard to know who might look fine but is actually __________. According to the National Institute of Mental Health, it takes the average person suffering with a ______ illness over ten years to ask for help. But there are very effective treatments. ___________ and therapy complement each other to _____ brain chemicals. In extreme cases, electroconvulsive _______, which is like a controlled seizure in the patient's _____, is also very helpful. Other promising treatments, like transcranial magnetic stimulation, are being investigated, too. So, if you know someone struggling with depression, encourage them, gently, to seek out some of these options. You might even offer to help with specific tasks, like looking up therapists in the area, or ______ a list of _________ to ask a doctor. To someone with depression, these first steps can seem ______________. If they feel guilty or ashamed, point out that depression is a _______ condition, just like ______ or diabetes. It's not a ________ or a personality trait, and they shouldn't expect themselves to just get over it anymore than they could will themselves to get over a broken arm. If you haven't experienced depression yourself, avoid comparing it to times you've felt down. Comparing what they're experiencing to normal, temporary ________ of sadness can make them feel guilty for struggling. Even just talking about depression ______ can help. For example, research _____ that asking someone about suicidal thoughts actually reduces their suicide risk. Open conversations about mental illness help erode ______ and make it easier for people to ask for help. And the more patients seek treatment, the more __________ will learn about depression, and the better the treatments will get.

Solution


  1. struggling
  2. mental
  3. medications
  4. boost
  5. feelings
  6. stigma
  7. making
  8. brain
  9. enjoy
  10. scientists
  11. medical
  12. shows
  13. close
  14. weeks
  15. hormones
  16. excessively
  17. depression
  18. openly
  19. diagnosis
  20. picture
  21. weakness
  22. world
  23. worthless
  24. complex
  25. illness
  26. deregulation
  27. questions
  28. therapy
  29. asthma
  30. specific
  31. hippocampal
  32. insurmountable
  33. symptoms

Original Text


Depression is the leading cause of disability in the world. In the United States, close to 10% of adults struggle with depression. But because it's a mental illness, it can be a lot harder to understand than, say, high cholesterol. One major source of confusion is the difference between having depression and just feeling depressed. Almost everyone feels down from time to time. Getting a bad grade, losing a job, having an argument, even a rainy day can bring on feelings of sadness. Sometimes there's no trigger at all. It just pops up out of the blue. Then circumstances change, and those sad feelings disappear. Clinical depression is different. It's a medical disorder, and it won't go away just because you want it to. It lingers for at least two consecutive weeks, and significantly interferes with one's ability to work, play, or love. Depression can have a lot of different symptoms: a low mood, loss of interest in things you'd normally enjoy, changes in appetite, feeling worthless or excessively guilty, sleeping either too much or too little, poor concentration, restlessness or slowness, loss of energy, or recurrent thoughts of suicide. If you have at least five of those symptoms, according to psychiatric guidelines, you qualify for a diagnosis of depression. And it's not just behavioral symptoms. Depression has physical manifestations inside the brain. First of all, there are changes that could be seen with the naked eye and X-ray vision. These include smaller frontal lobes and hippocampal volumes. On a more microscale, depression is associated with a few things: the abnormal transmission or depletion of certain neurotransmitters, especially serotonin, norepinephrine, and dopamine, blunted circadian rhythms, or specific changes in the REM and slow-wave parts of your sleep cycle, and hormone abnormalities, such as high cortisol and deregulation of thyroid hormones. But neuroscientists still don't have a complete picture of what causes depression. It seems to have to do with a complex interaction between genes and environment, but we don't have a diagnostic tool that can accurately predict where or when it will show up. And because depression symptoms are intangible, it's hard to know who might look fine but is actually struggling. According to the National Institute of Mental Health, it takes the average person suffering with a mental illness over ten years to ask for help. But there are very effective treatments. Medications and therapy complement each other to boost brain chemicals. In extreme cases, electroconvulsive therapy, which is like a controlled seizure in the patient's brain, is also very helpful. Other promising treatments, like transcranial magnetic stimulation, are being investigated, too. So, if you know someone struggling with depression, encourage them, gently, to seek out some of these options. You might even offer to help with specific tasks, like looking up therapists in the area, or making a list of questions to ask a doctor. To someone with depression, these first steps can seem insurmountable. If they feel guilty or ashamed, point out that depression is a medical condition, just like asthma or diabetes. It's not a weakness or a personality trait, and they shouldn't expect themselves to just get over it anymore than they could will themselves to get over a broken arm. If you haven't experienced depression yourself, avoid comparing it to times you've felt down. Comparing what they're experiencing to normal, temporary feelings of sadness can make them feel guilty for struggling. Even just talking about depression openly can help. For example, research shows that asking someone about suicidal thoughts actually reduces their suicide risk. Open conversations about mental illness help erode stigma and make it easier for people to ask for help. And the more patients seek treatment, the more scientists will learn about depression, and the better the treatments will get.

Frequently Occurring Word Combinations


ngrams of length 2

collocation frequency
mental illness 2
feel guilty 2



Important Words


  1. ability
  2. abnormal
  3. abnormalities
  4. accurately
  5. adults
  6. anymore
  7. appetite
  8. area
  9. argument
  10. arm
  11. ashamed
  12. asthma
  13. average
  14. avoid
  15. bad
  16. behavioral
  17. blue
  18. blunted
  19. boost
  20. brain
  21. bring
  22. broken
  23. cases
  24. change
  25. chemicals
  26. cholesterol
  27. circadian
  28. circumstances
  29. clinical
  30. close
  31. comparing
  32. complement
  33. complete
  34. complex
  35. concentration
  36. condition
  37. confusion
  38. consecutive
  39. controlled
  40. conversations
  41. cortisol
  42. cycle
  43. day
  44. depletion
  45. depressed
  46. depression
  47. deregulation
  48. diabetes
  49. diagnosis
  50. diagnostic
  51. difference
  52. disability
  53. disappear
  54. disorder
  55. doctor
  56. dopamine
  57. easier
  58. effective
  59. electroconvulsive
  60. encourage
  61. energy
  62. enjoy
  63. environment
  64. erode
  65. excessively
  66. expect
  67. experienced
  68. experiencing
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  70. eye
  71. feel
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  78. genes
  79. gently
  80. grade
  81. guidelines
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  83. hard
  84. harder
  85. health
  86. helpful
  87. high
  88. hippocampal
  89. hormone
  90. hormones
  91. illness
  92. include
  93. institute
  94. insurmountable
  95. intangible
  96. interaction
  97. interest
  98. interferes
  99. investigated
  100. job
  101. leading
  102. learn
  103. lingers
  104. list
  105. lobes
  106. losing
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  108. lot
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  110. magnetic
  111. major
  112. making
  113. manifestations
  114. medical
  115. medications
  116. mental
  117. microscale
  118. mood
  119. naked
  120. national
  121. neuroscientists
  122. neurotransmitters
  123. norepinephrine
  124. normal
  125. offer
  126. open
  127. openly
  128. options
  129. parts
  130. patients
  131. people
  132. person
  133. personality
  134. physical
  135. picture
  136. play
  137. point
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  144. questions
  145. rainy
  146. recurrent
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  148. rem
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  150. restlessness
  151. rhythms
  152. risk
  153. sad
  154. sadness
  155. scientists
  156. seek
  157. seizure
  158. serotonin
  159. show
  160. shows
  161. significantly
  162. sleep
  163. sleeping
  164. slowness
  165. smaller
  166. source
  167. specific
  168. states
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  170. stigma
  171. stimulation
  172. struggle
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  174. suffering
  175. suicidal
  176. suicide
  177. symptoms
  178. takes
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  180. tasks
  181. temporary
  182. ten
  183. therapists
  184. therapy
  185. thoughts
  186. thyroid
  187. time
  188. times
  189. tool
  190. trait
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  192. transmission
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  195. trigger
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  199. volumes
  200. weakness
  201. weeks
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  203. world
  204. worthless
  205. years